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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK9
All Species:
13.03
Human Site:
S749
Identified Species:
28.67
UniProt:
Q8TD19
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD19
NP_149107.4
979
107168
S749
I
G
T
V
F
Q
S
S
S
P
G
G
G
G
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097546
979
107204
S749
I
G
T
V
F
Q
S
S
S
P
G
G
G
G
G
Dog
Lupus familis
XP_547912
974
106819
C749
I
R
T
V
G
S
Q
C
S
S
G
G
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1R7
984
107065
S749
I
G
T
V
V
Q
S
S
S
P
G
G
G
I
G
Rat
Rattus norvegicus
NP_001100217
958
104862
S748
I
G
T
V
V
Q
S
S
S
P
G
G
R
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506669
536
57599
S332
V
S
E
T
P
D
P
S
G
G
F
R
G
T
M
Chicken
Gallus gallus
XP_001235085
1086
118657
C861
I
G
T
V
T
Q
S
C
T
T
G
G
G
E
E
Frog
Xenopus laevis
Q7ZZC8
944
104521
C731
I
G
T
L
A
Q
S
C
S
S
G
G
S
G
S
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
P493
T
Q
D
S
H
N
C
P
Q
Q
V
S
L
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781356
721
79856
K517
K
V
T
F
Q
G
K
K
E
I
K
T
V
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXT4
555
62879
A351
V
P
Q
R
Q
E
E
A
K
K
Q
S
G
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
95.7
N.A.
95
93.6
N.A.
44.8
76
69.5
24.1
N.A.
N.A.
N.A.
N.A.
40.2
Protein Similarity:
100
N.A.
99.4
96.8
N.A.
96.4
95
N.A.
48.9
81.4
80.1
41
N.A.
N.A.
N.A.
N.A.
52.8
P-Site Identity:
100
N.A.
100
60
N.A.
86.6
80
N.A.
13.3
60
60
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
60
N.A.
86.6
80
N.A.
20
66.6
66.6
0
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
28
% A
% Cys:
0
0
0
0
0
0
10
28
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
10
0
10
0
0
0
0
10
10
% E
% Phe:
0
0
0
10
19
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
55
0
0
10
10
0
0
10
10
64
64
64
37
46
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
64
0
0
0
0
0
0
0
0
10
0
0
0
19
0
% I
% Lys:
10
0
0
0
0
0
10
10
10
10
10
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
10
10
0
37
0
0
0
10
0
% P
% Gln:
0
10
10
0
19
55
10
0
10
10
10
0
0
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
0
0
0
10
10
0
0
% R
% Ser:
0
10
0
10
0
10
55
46
55
19
0
19
10
10
10
% S
% Thr:
10
0
73
10
10
0
0
0
10
10
0
10
0
10
0
% T
% Val:
19
10
0
55
19
0
0
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _